Research Trends

  Acute lymphoblastic leukemia (ALL) is a very rare (0.1 in 10,000) cancer condition that results from the invasion of immature lymphocytes or leukocytes into the bone marrow during childhood. According to Leukemia and Lymphoma Society’s 2018-2019 facts, the incidence of acute lymphoblastic leukemia was 7.8 (per 100,000) in children aged 1-4 years during 2011-2015. Italy, the U.S. Switzerland, and Costa Rica are the countries with the highest incidence of ALL. ALL most commonly occurs in young children and adolescents who have one unaffected parent who has an inherited thalassemia or anemia. Studies indicate that many of these children will develop an illness characterized by fever, generalized fatigue, or swollen lymph nodes and may even suffer from lymphedema. Acute lymphoblastic leukemia therapeutics generally begin with a combination treatment approach. This treatment usually involves combinations of chemotherapy, radiation therapy, surgery, and targeted drug therapy. A combinat