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Clomiphene Citrate is one of the potential anti-estrogen drug that is commonly prescribed to women suffering with infertility

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  Clomiphene Citrate is a derivative of the mineral called selenium, is a synthetic estrogen receptor modulator (receptor modulator), first developed for the treatment of female reproductive dysfunction in women. The compound has been shown to reduce estrogen production by up to 50% in some studies, though it has not been approved by the FDA as estrogen therapy or a "pregnancy drug". Some experts feel that the safety profile of CC is still being explored and that more research is needed. One type of adverse reaction that has been noted is a headache. This is not too surprising because many of the studies of CC involved women of childbearing age who were taking hormone replacement therapy for contraception and/or to prevent premenstrual symptoms. Women diagnosed with the condition of endometriosis, a disorder in which tissue from the lining of the uterus is abnormally shaped and grows into the abdominal cavity, may also benefit from the use of clomiphene esters as an adjunct