Recurrent Glioblastoma Multiforme Treatment; Surgery Is the Mainstay of Treatment for Recurrent Glioblastoma Multiforme

 

Recurrent Glioblastoma Multiforme Treatment

There is no standard recurrent glioblastoma multiforme treatment. Surgery, when feasible, is recommended, but no robust data supporting an increase in survival are available. Glioblastoma multiforme (GBM) is an aggressive and the most common form of brain cancer that involves glial cells. It is a grade 4 glioma brain tumor arising from brain cells called glial cells. A grade of a brain tumor describes how likely the tumor is to grow and spread. Grade 4 is the most aggressive and serious type of tumor.

Glioblastoma multiforme is a heterogeneous group of tumors (it behaves differently in different people) and can vary when it comes back or recurs. It has a tendency to recur within 6-8 months in most patients. Although there is no standard recurrent glioblastoma multiforme treatment, patients with this malignancy have many treatment options available to them. Glioblastoma’s charge their way into normal brain tissue diffusely and erratically, which makes them surgical nightmares. Signs and symptoms of GBM include seizures, headache, double or blurred vision, vomiting, and difficulty in speaking.

Despite initial treatment with chemotherapy, radiotherapy (or radiation therapy), and surgical resection, GBM virtually always recurs. Surgery is sometimes recommended for the recurrent glioblastoma multiforme treatment. Recurrent glioblastoma multiforme (GBM) is a possibility of reoccurrence of glioblastoma multiforme after tumor surgery. This is because it is difficult to remove the tumor during surgery and there is always possibility that the cancer may occur after some time. Thus, the demand for safe and effective recurrent glioblastoma multiforme treatment has increased worldwide.

Glioblastoma (or GBM) is one of the most complex, deadly, and treatment-resistant cancers. Median age of diagnosis is 64 years and it is more common in men as compared to women. According to the National Brain Tumor Society, more than 13,000 people in the United States were expected to receive a GBM diagnosis in 2020. Moreover, it is estimated that more than 10,000 Americans will succumb to glioblastoma every year. The frontline treatment for GBM is surgery, followed by radiation therapy and chemotherapy.


Location: India

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