U.S. Meibomian Gland Dysfunction Market Driven by High Prevalence of Meibomian Gland Dysfunction in the Country

 

U.S. Meibomian Gland Dysfunction

Meibomian glands are small oil glands, which line the margin of the eyelids. These glands produce meibum, an oily substance that prevents evaporation of the eye's tear film. The oil coats the surface of the eyes and keeps the water component of our tears from evaporating. The gland is located in the superior and inferior tarsal plates. A number of eye problems can involve the meibomian glands, which include, blepharitis, dry eye, and Sjögren's syndrome.

Meibomian gland dysfunction (MGD) is characterized by the inability of glands in secreting enough oil. The condition can also emerge when the oil secreted by the glands is of poor quality. MGD can lead to altered tear film composition, ocular surface disease, ocular and eyelid discomfort, and evaporative dry eye. Meibomian gland dysfunction is the leading cause of evaporative dry eye disease. It affects over 30 million adults in the U.S. alone. In patients with no ocular symptoms, the prevalence of MGD reached 41.7% across all ages, 47.8% in the elderly, and 35.76% in pediatric/young adult populations (July 2019 ARVO Annual Meeting Abstract). Thus, significant prevalence of MGD is expected to propel growth of the U.S. meibomian gland dysfunction market. 

In March 2021, Azura Ophthalmics Ltd., a clinical-stage company headquartered in Tel Aviv-Yafo, Israel with operations in Australia and the U.S., announced topline results from a phase 2 program evaluating the company’s investigational therapy for the treatment of MGD. Earlier in October 2020, Azura Ophthalmics Ltd. raised US$ 20 million for the development of pipeline of new chemical entities in pre-clinical through Phase 2 development for other significant ocular surface conditions. Investment in R&D is thus expected to aid in growth of the U.S. meibomian gland dysfunction market.    


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