Abortion Drugs; Mifepristone and Misoprostol; Used For Pregnancy Termination

 

Abortion Drugs

Abortion drugs, also known as a medical abortion, are drugs used to bring about an abortion. The recommended regimen usually consists of a combination of drugs, mifepristone followed by misoprostol. Abortion drugs have many benefits, especially for women who have chosen this method to terminate their pregnancy. However, it has some drawbacks, the procedure may be life-threatening, and there is a high risk of death due to complications during the procedure. Moreover, it can also cause pelvic inflammatory disease.

The World Health Organization (WHO) recommends mifepristone 200 mg by mouth followed by misoprostol 800 mcg vaginally, inside the cheek, or under the tongue. The success rate of this recommended combination is 96.6%, through 10 weeks pregnancy. In contrast to provider-administered abortion drugs, self-administered abortion drugs are also available, where women take abortion drugs without direct medical supervision. Self-administered abortion drugs may be as effective as provider-administered drugs but the safety aspects remain uncertain.

For women who prefer this method for terminating a pregnancy, it is important to understand the possible complications from it. This method has the highest rate of complications in the second trimester, and these include excessive bleeding, infection, uterine contractions, and even death. The most common complications happen in the last period or shortly after the end of the first period. These include excessive bleeding, infection, uterine contractions, and death. The excessive bleeding is caused because of hormonal changes. Although complications do occur, this is often not fatal and there are very low chances of death occurring.

Misoprostol is sometimes used to decrease blood loss after delivery of a baby. However, the U.S. Food and Drug Administration (FDA) has approved misoprostol only for the prevention and treatment of NSAID-induced gastric ulcers in patients taking NSAIDs (Nonsteroidal anti-inflammatory drugs) and at high risk for ulceration. Whereas, Mifepristone was approved for abortion in the U.S. by the FDA in September 2000. It is legal and available in all 50 states.


Location: India

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