Demand for Tuberculosis Drugs to Surge with Increasing Prevalence of Tuberculosis and Increasing Number of Smokers

 

Tuberculosis Drugs

Tuberculosis is an infectious disease that commonly infects the lungs and causes pulmonary fibrosis (pus in the blood). Other organs, including the bladder, kidneys, or heart can also be affected. If left untreated, symptoms can progress and eventually lead to death. The disease is spread through direct contact with infectious material such as blood, saliva, and other secretions from the nose, mouth, or rectum. Tuberculosis can have many forms and is usually caused by several strains of a single bacterium, Mycoplasma Tuberculosis (MTB).

Increasing number of smokers is expected to boost demand for TB drugs. According to the World Health Organization, 1.337 billion people smoked tobacco worldwide in 2018. Moreover, according to the 2018 National Survey on Drug Use and Health, in the U.S., around 164.8 million people aged 12 or older in the U.S. were past month substance users that included tobacco, alcohol, or illicit drugs. The most commonly used tuberculosis drugs include, Isoniazid, Rifampin (Rifadin, Rimactane), Ethambutol (Myambutol), and Pyrazinamide. Isoniazid, also known as isonicotinic acid hydrazide, is an antibiotic used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol for the treatment of tuberculosis. Rifampicin, also known as rifampin, is an antibiotic used to treat several types of bacterial infections, including tuberculosis, Mycobacterium avium complex, leprosy, and Legionnaires’ disease.

Recent findings demonstrated how the enzyme inhibitor triaza-coumarin, or TA-C, is metabolized by the TB germs. The development offers potential in new tuberculosis drugs that are effective in inhibiting the disease from within. In other research, a team at the University of Salford in the United Kingdom discovered that an already licensed medicine may be used to cut off their fuel supply while leaving healthy cells undamaged. The team assessed the efficacy of an FDA-approved tuberculosis drug called Sirturo. In vivo animal experiments showed that the drug could target the fuel supply of these ultra-fit cancer cells and selectively create a "power failure" in them, while leaving healthy cells unharmed.

Moreover, increasing prevalence of tuberculosis is expected to boost demand for tuberculosis drugs. According to the World Health Organization, in 2018, India reported around 2.69 million cases of tuberculosis.


Location: India

Comments

Post a Comment

Popular posts from this blog

Light Linear Alpha Olefins Are Produces through Oligomerization of Ethylene and by Fischer-Tropsch Synthesis

Image
  Light linear alpha olefins are commonly manufactured by two main routes: oligomerization of ethylene and by Fischer-Tropsch synthesis followed by purification. They are manufactured for a variety of reasons. One such reason is to use them as fabric and other textile applications in clothing manufacture. Various companies use ethylene trimerization process that produces only 1-hexene. In the U.S., Chevron Phillips Chemical Company, LLC, uses this process. Another commercial process, offered by a technology licensor IFP, dimerizes ethylene to high purity 1-butene. There are a wide range of applications for light linear alpha olefins . They are predominantly use in production of polyethylene, linear aldehyde, fatty acids, linear alcohols. Alpha olefins are also used in production of synthetic lubricant basestock and to make surfactants in a blend with higher linear alpha olefins. Another common use of light linear alpha olefins includes printing and apparel industries, agriculture
Read more

Cervical Cancer Diagnostic Tests have become highly sophisticated with accurate diagnosis for effective treatment

Image
  There are three basic types of cervical cancer namely squamous cell carcinoma (also known as cancer of the cervix), adenocarcinoma, and carcinoma in the fallopian tubes. Adenocarcinomas are the most common type and usually begin as a non-cancerous tissue. Squamous cell carcinomas (also called vaginal cancer of the cervix) develop primarily in the outer lining of the cervix and is normally found in 90 to 95% of cervical cancer cases. One of the key cervical cancer diagnostic tests are HPV diagnostic test and they are at an all-time high. As previously stated, research reports continue to indicate that the future is not likely to see a slowing of the rate of new infections, but instead an acceleration into the future. The Information presented in this article briefly outlines two of the most important players in the cervical cancer diagnostic tests sales, price and growth rate of HPV. A recent development in DNA cervical cancer diagnostic tests makes it possible to determine if a pe
Read more

Beta Glucan-based products have been shown to be effective in lowering cholesterol and preventing heart disease

Image
  Beta glucan based products have been being used for the most recent decade. These are significant leap forwards in present day clinical history. Beta glucan is gotten from plant sources and has been utilized for quite a long time to assist wellbeing. It is nothing unexpected that this compound has as of late discovered its way into the nourishing enhancements field. It is perhaps the most nutritious enhancements available. Exploration has shown that individuals who burn-through Glucan based products have lower paces of coronary illness. It is accepted that the part of the enhancement helps support the insusceptible framework and expands the body's resilience to low degrees of cholesterol. This permits the body to all the more proficiently eliminate overabundance cholesterol from the circulatory system. Besides, the fixings in these products are high in cancer prevention agents, which help forestall cell harm. Studies have shown that Glucan products can help diminish joint irrit
Read more