Chronic Liver Diseases Treat the Acute Symptoms of the Disease and Prevent Condition from Progressing

 

Chronic Liver Diseases Therapeutics

Chronic liver disease cannot be cured. Hence, chronic liver diseases therapeutics, such as liver transplant, are important to prevent further exacerbation of the disease. There are several types of liver diseases such as hepatitis A, hepatitis B, and hepatitis C; liver cancer; liver fibrosis, hemochromatosis; fatty liver disease and cirrhosis; and Wilson’s disease. Therefore, with the increasing prevalence of chronic liver diseases, demand for chronic liver diseases therapeutics is also increasing with a rapid pace, worldwide.

According to the Japan Society of Hepatology, Japan has one of the highest rates of liver cancer, and the annual mortality rate is increasing rapidly. Death rate of Japan increased from 6.5 per 1,000 people in 1971 to 10.9 per 1,000 people in 2020, growing at an average annual rate of 1.06%. Thus, there is an increasing demand for chronic liver diseases therapeutics in Japan. However, there are some side effects and risks associated with liver disease therapeutics, such as headache, nausea, loss of appetite, fever, and drug-induced liver disease.

Moreover, trientine, oral zinc, and unithiol have all shown promise as therapeutic alternatives. Cyclosporin has also produced clinical improvement in several case reports but no comparison has yet been made with the current standard therapy. In some cases, a liver transplant may be needed, while other treatments may be specific to the cause of the disease. There are different modalities of treatment for each category of chronic liver disease. Appropriate medication, use of prescribed drugs, and lifestyle changes are standard line chronic liver diseases therapeutics.

They are mainly aimed at treating the acute symptoms of the diseases and preventing further progression of the condition. Liver diseases can be either acute or chronic. The early stages of liver failure can often heal over time with proper treatment and lifestyle changes. Other liver problems may be treated with medications or may require surgery.


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