Chronic Liver Diseases Treat the Acute Symptoms of the Disease and Prevent Condition from Progressing
Chronic liver disease cannot be cured. Hence, chronic liver
diseases therapeutics, such as liver transplant, are important to prevent
further exacerbation of the disease. There are several types of liver diseases
such as hepatitis A, hepatitis B, and hepatitis C; liver cancer; liver
fibrosis, hemochromatosis; fatty liver disease and cirrhosis; and Wilson’s
disease. Therefore, with the increasing prevalence of chronic liver diseases,
demand for chronic liver diseases therapeutics is also increasing with a rapid
pace, worldwide.
According to the Japan Society of Hepatology, Japan has one
of the highest rates of liver cancer, and the annual mortality rate is
increasing rapidly. Death rate of Japan increased from 6.5 per 1,000 people in
1971 to 10.9 per 1,000 people in 2020, growing at an average annual rate of
1.06%. Thus, there is an increasing demand for chronic
liver diseases therapeutics in Japan. However, there are some side
effects and risks associated with liver disease therapeutics, such as headache,
nausea, loss of appetite, fever, and drug-induced liver disease.
Moreover, trientine, oral zinc, and unithiol have all shown
promise as therapeutic alternatives. Cyclosporin has also produced clinical
improvement in several case reports but no comparison has yet been made with
the current standard therapy. In some cases, a liver transplant may be needed,
while other treatments may be specific to the cause of the disease. There are
different modalities of treatment for each category of chronic liver disease.
Appropriate medication, use of prescribed drugs, and lifestyle changes are
standard line chronic liver diseases therapeutics.
They are mainly aimed at treating the acute symptoms of the
diseases and preventing further progression of the condition. Liver diseases
can be either acute or chronic. The early stages of liver failure can often
heal over time with proper treatment and lifestyle changes. Other liver
problems may be treated with medications or may require surgery.
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