Carboxymethyl Cellulose; Used To Treat Irritation and Discomfort Due To Dryness of the Eyes

 

Carboxymethyl Cellulose

Carboxymethyl cellulose, also known as cellulose gum, is a cellulose derivative bound to some of the hydroxyl groups of the glucopyranose monomers which make up the cellulose backbone. It is sometimes also used as its sodium salt, sodium carboxymethyl cellulose. Carboxymethyl cellulose is used in various end-use industries, such as oil & gas, paper processing, agriculture, paint, pharmaceutical, and food & beverages, others. It is chemically stable and physiologically inert, odorless, and tasteless substance, safe for both the environment and the health.

Carboxymethyl cellulose is extensively used as binder, dispersant, stabilizer, and thickener in the aforementioned industries. It is a type of thickener and stabilizer used in food like milk, ice cream, and some baked goods. Other uses include chemicals, laundry detergents, dyeing, paper and ink making, and oil drilling. Plant-derived cellulose, monochloroacetic acid, and caustic soda are some of the major raw materials used to manufacture carboxymethyl cellulose.

Moreover, it is used in the treatment of dry eyes. It is used as a lubricant to relive irritation and discomfort due to dryness of the eyes or exposure of the eyes to wind or sun. Furthermore, carboxymethyl cellulose is the United States Food and Drug Administration (FDA) approved Ophthalmologic Agent that is used to treat burning, irritation, and discomfort due to dryness of the eye. Common adverse reactions include eye pain, changes in vision, irritation of the eye.

Cellulose is extracted from sugarcane bagasse through the elimination of hemicellulose and lignin; then by using sodium monochloroacet and various sodium hydroxide concentrations, it is converted to carboxymethyl cellulose. The material exhibits gradual biodegradability and can be incinerated after use, making it a very environmentally friendly material. However, a wide variety of alternatives, such as such as ethylcellulose, methylcellulose, guar gum, and hydroxypropyl cellulose, are available in the market, all of which have similar properties and can replace carboxymethyl cellulose in numerous applications.


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