Procalcitonin Antibody; Used To Diagnose the Level of Procalcitonin (PCT) In the Body

 

Procalcitonin Antibody

Procalcitonin antibody test is used to diagnose the level of procalcitonin in the body, with the help of wet lab analysis. Procalcitonin is a naturally occurring peptide composed of amino acids which are known as the proline, glycine, arginine, and valine. This particular peptide is found in the human blood and helps in the production of polysaccharides which are part of the immune system. Procalcitonin is produced in response to an antigen, which is known as the calcitonin gene-related antigen. The procalcitonin antibody has recently emerged as one of the most effective treatments for patients with chronic obstructive pulmonary disease.

There are two types of the procalcitonin antibody, such as polyclonal procalcitonin antibody and monoclonal procalcitonin antibody. Studies have shown that the polyclonal antibodies help reduce lung inflammatory response to activated interferon and amyloid protein. Procalcitonin exhibits greater specificity than other proinflammatory markers in identifying patients with sepsis and can be used in the diagnosis of bacterial infections. Microbial infected individuals and procalcitonin variance in healthy individuals has increased the use of the procalcitonin antibody to improve bacterial infection identification and develop antibiotic therapy.

Thus, with the increasing prevalence of chronic diseases such as HIV, tuberculosis, sepsis, and hepatitis, the demand for procalcitonin antibody is also increasing. According to the Centers for Disease Control and Prevention (CDC), in 2019, the majority (51%) of TB cases continued to be reported from 4 states: Florida (6.3%), New York (8.5%), Texas (13.0%), and California (23.7%). While, in 2018, around 542 deaths in the United States were attributed to TB. This is an increase from 515 deaths attributed to TB in 2017. Thus, with the increasing prevalence of aforementioned chronic diseases, the demand for procalcitonin antibody is also increasing.

Procalcitonin antibody test is used to determine the risk that a critically ill person will progress to severe sepsis and septic shock, or the risk of the person dying. Moreover, the test is used to distinguish between bacterial and non-bacterial causes of infections, such as pneumonia and meningitis. The higher the procalcitonin level, the more severe the infection.


Location: India

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