Prepacked chromatography columns remain one of the critical devices in the biopharmaceutical industry for protein purification

 

Prepacked Chromatography Columns

Recently, large-scale, prepackaged chromatography columns for analytical testing have become available to commercial and clinical production, and they represent an emerging trend in the analytical market. For decades, analytical test columns were essentially single-use devices. As technology advanced, it became necessary to replace single-use column systems with more complex, durable, and cost-effective two-dimensional columns that could better withstand high temperatures and pressures. Now, instead of buying an expensive analytical chromatography system with expensive accessories, several companies are providing their customers with ready-to-use, customized, and semi-customizable analytical chromatography columns.

The increasing demand for ready-to-use chromatography columns is driven by improved analytical efficiency, simplified laboratory operations, and streamlined laboratory cost management. As a result, several companies in the analytical market have experienced phenomenal growth in business growth, while sales revenues have been growing at double digits year-over-year. Prepacked chromatography columns represent an attractive alternative to the single-user, high-cost commercial models that can be cumbersome and costly to install, operate and maintain. The prepacked chromatography columns line represents an ideal solution to address the growing needs of the analytical market for cost-effective, versatile, and durable analytical Chromatography and Multicaustion coupled with performance and accuracy, reliability, and ease of use.

Chromatography columns come in various forms and sizes and the features they have generally depend upon their application. In the case of desktop models, the column width varies from less than 100mm to more than a kilometer. The range of sample flow rate depends on the type of column and its external dimensions. The average particle size ranges from a few micrometers to several tens of millimeters. The sample flow rate determines how fast the droplets collect in the Columns and the concentration of the analyte present in the sample.


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