Stem cell technology is emerging as one of the Mucopolysaccharidosis (MPS) treatment
Mucopolysaccharides
are more popularly known are long linear, non-repetitious polysaccharide units
containing at least one non-lactose sugar with an attached galactose sugar. The
repeating two-dimensional sugar unit is composed of amino acid and uric acid,
excluding mucopolysaccharides, where in place of the amino acid it contains
galactose; the non-galactose sugar, on the other hand, is either glucose or
galactose.
Mucopolysaccharides
are produced in the intestines through a series of events. First, the ingested
food supplies the enzymes required for glycolysis, the process that produces
energy from glucose. Glucose is transported to the liver for conversion into
glycogen, a material that stores fat and prevents glycolysis from being
inhibited. The liver then transports the glycogen back to the small intestine
where it is incorporated into long chains of glucose-free glucose and
transported back into the bloodstream. These long chains eventually exit the
body in the urine.
Mucopolysaccharides
have also been shown to inhibit the growth of tumors and to promote cancerous
treatment by inhibiting tumor metastasis and by preventing tumor immune cells
from damaging the host tissue. In addition, mucopolysaccharides have been found
to prevent allergic reactions in people with allergies.
The
most common causes of mucopolysaccharide-induced nephritis include viral
infections, chemicals, and drugs. Mucopolysaccharides may also result from
certain cancers like breast cancer and lung cancer. Mucopolysaccharide is
produced by the myeloid leukemia cells and may provoke symptoms like fever,
weight loss, and joint and skin rashes.
Research
activities upholding stem cell technology application in Mucopolysaccharidosis
(MPS) Treatment research in North America, the most promising drugs are
the ones that are derived from mucopolysaccharide. These drugs, which are now
under phase II of clinical trials, are said to be capable of reducing the activity
of Mucopolysaccharides in body cells that generate it, which can lead to
preventing or slowing down the growth of certain cancer cells like leukemia and
renal cell carcinoma. By using this Mucopolysaccharidosis (MPS) treatment,
scientists can hope to find out how this substance affects the ability of
cancerous cells to survive.
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