Machine Learning Can Significantly Impact Sepsis Diagnostics, Which Has Led To Significant Investment in the Field

 

Sepsis Diagnostic

Sepsis diagnostics is the term given to a generic medical diagnostics for a specific condition that causes fluid accumulation in the lower parts of the body. The exact cause of the condition remains unknown to most doctors; however, the most common cause is bacterial infection. Common symptoms include a high fever, nausea, chills, vomiting, diarrhea and stomach pain. These symptoms are generally caused by the body's attempt to combat foreign matters that are known to be harmful to health.

High prevalence of sepsis is expected to boost demand for sepsis diagnostics. According to the study, ‘Epidemiology of neonatal early-onset sepsis in a geographically diverse Australian health district 2006-2016’, published in PLOS One in 2019, among 93,584 live born babies, 65 had confirmed early-onset sepsis (0.69/1000 live births).

Machine learning can significantly impact sepsis diagnostics, which has led to significant investment in the field. In October 2019,         the Biomedical Advanced Research and Development Authority, U.S. Department of Health and Human Services, awarded Beckman Coulter, Inc. a contract of US$ 1.25 million to develop and commercialize a novel machine-learning-based sepsis detection algorithm. Hematology analyzers play a major role in diagnosis of sepsis. In May 2020,    Beckman Coulter launched its DxH 690T hematology analyzer featuring mid-volume laboratories advanced features such as the Early Sepsis Indicator in the U.S. Earlier, in April 2019, the company also received 510(k) clearance from the U.S. Food and Drug Administration for its Early Sepsis Indicator, a hematology-based cellular biomarker that is designed to help emergency department physicians identify patients with sepsis or at increased risk of developing sepsis.

Blood gas analyzers are used in identifying sepsis biomarkers. In September 2019, Radiometer Ltd. demonstrated its range of point of care solutions at the Institute of Biomedical Science (IBMS) Congress 2019, held in the U.K., with new features such as ABL90 FLEX PLUS blood gas analyzer with creatinine and urea and AQT90 FLEX immunoassay analyzer including sepsis biomarkers.


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