Ketorolac; a Medicine Prescribed to Treat Moderate to Severe Acute Pain, Usually After Surgery
Ketorolac is a non-steroidal anti-inflammatory drug (NSAID)
used to the treatment of pain. It is recommended for moderate to severe pain. Ketorolac
helps to prevent blood clots, decrease fever, and in higher doses, decrease
inflammation. However, there are some side effects, which depend on the
specific drug but largely include the risk of kidney disease, heart attack, and
gastrointestinal ulcers and bleeds. Thus, before beginning a regimen of
ketorolac or any other anti-inflammatory prescription medication, one should
discuss the risks with the doctor.
Moreover, one should not take ketorolac with other drugs such
as probenecid, pentoxifylline, aspirin, or another anti-inflammatory. Ketorolac
can also result in stomach or intestinal upset, which is potentially fatal if
it occurs without warning. One should also not use ketorolac when they are on
other forms of treatment, such as severe kidney disease. For instance, if
someone has been diagnosed with acute hepatitis C, avoid taking ketorolac along
with an anti-fungal medication such as ciprofloxacin or penicillin. Thus, it is
important to consult a doctor before starting a regimen of NSAIDs such as ketorolac.
Ketorolac help reduce hormones that cause inflammation and
pain in the body. It is used for the short-term treatment of moderate to severe
pain in adults. Intravenous ketorolac given at the end of surgery is more
effective than oral acetaminophen or oral ibuprofen. Pain relief can be
achieved before intravenous delivery compared to oral agents. Thus, it is
widely used before or after medical procedures or after surgery. Ketorolac
(Toradol) has been effectively used to treat postoperative pain for several decades.
However, its use is limited to a 5-day treatment duration due to an increased
risk of gastrointestinal bleeding.
Ketorolac has diversified medicinal use such as, used in
treatment of dysmenorrhea, controls pain without affecting respiration in infants,
and used as eye drop during eye surgery to surge pain in patients. Thus, with
increasing utilization of Ketorolac in different medical conditions, the demand
for Ketorolac is also increasing.
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