Quick Overview of Organosulfur Compounds and Their Anti-inflammatory Effects in Human Health
Organosulfur chemicals are organic compounds that contain
sulfur as a primary component. They are often associated with foul odors, but
most of them are known as organosulfur derivatives, such as saccharin. Methionine
and cysteine, out of 20 common amino acids, are organosulfur compounds.
Furthermore, organosulfur compounds are classified into several groups depending
on the amount of sulfur they contain. Organic compounds can be used instead to
create sweetness; the result is comparable in taste to that of natural honey.
Organosulfur
compounds are widely present in the human bodies and the natural
environment. An organosulfur compound contains at least one carbon-sulfur bond.
Organosulfur compounds are usually present in fruits, vegetables, pulses
(legumes), cereals (grains), and other plant foods. These compounds are mostly
found in cruciferous vegetables such as onion, garlic, brussel sprouts,
cauliflower, and broccoli. These compounds are widely consumed by the general
population, with well-documented benefits.
Moreover, organosulfur compounds can not only act as direct
antioxidants that trap electrons, but may also have non-antioxidant effects,
such as antiaging actions, immunomodulatory, anti-inflammatory, fibrinolytic,
and antiplatelet. These compounds display anti-tumor, anti-fungal, and antimicrobial
capabilities that expands their therapeutic applications. These properties are
useful in the prophylaxis and treatment of various pathological states, such as
diabetes, neurodegenerative disorders, cancer, and cardiovascular diseases.
With increasing use of organosulfur compounds for
therapeutics, the demand for organosulfur compounds is also increasing. Hydrogen
sulfide is considered an important biological mediator, and is widely diagnosed
in patients with low levels of hydrogen sulfide. Organosulfur compounds help
stabilize high blood pressure and blood sugar, as well as enhance immunity.
Moreover, there is huge demand for organosulfur compounds in various end-use
industries. For example, China exports of organosulfur compounds to Mexico during
2019 were US$ 51.71 Million, according to the United Nations COMTRADE database
on international trade.
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